Acorn Personalized Secretome Treatment

This innovative, cell-free topical serum is derived from the bioactive secretome—an ultra-concentrated blend of proteins, growth factors, exosomes, cytokines, and structural molecules taken from your own hair follicle stem cells.

The process begins with a simple in-office collection of around 50 hair follicles. These are sent to a state-of-the-art lab where the stem cells are cultured and cryopreserved. The resulting secretome is then freeze-dried into a shelf-stable format and rehydrated with hyaluronic acid. The serum is applied topically following treatments like microneedling or laser resurfacing, with additional product provided for at-home use over the next one to two weeks.

The benefits of this personalized serum are exceptional. Because it comes from your own biology, there is minimal risk of irritation or reaction. Clinical data shows it contains dozens of times more regenerative factors than traditional platelet-rich plasma, helping to speed up recovery, reduce inflammation, and improve hydration, firmness, tone, and skin texture. Patients report faster healing, reduced redness, and better overall post-treatment results.

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Dr. Steven Swengel
Dr. Steven Swengel
Board-Certified Dermatologist

Since establishing RefinedMD in 2012, Dr. Swengel has earned a reputation throughout the South Bay as one of the area’s top cosmetic and medical dermatologists. He is sought out for his expertise as a Mohs micrographic surgeon and laser treatment specialist, as well as his warm, attentive style of patient care.

Meet Dr. Steven Swengel
Dermatologist
Board-Certified Dermatologist

A Reputation Built on Results

Dr Roy does amazing work. He is a true artist. He thoroughly explained the procedure, very helpful with...
Fabulous polite, professional and highly skilled Doctors and staff. Have had several Halo laser treatments...
Refined MD has been my go-to destination for aesthetic treatments for nearly four years, and I couldn't...
RefinedMD has been my go-to for all things skincare for years! They have top-of-the-line equipment,...

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This treatment is ideal for anyone looking to amplify the effects of aesthetic procedures or address early signs of aging and hair thinning. As an added bonus, your preserved stem cells remain banked for future use as regenerative technologies continue to advance.

Schedule your consultation at RefinedMD today to learn how Acorn Personalized Secretome Treatment can unlock the regenerative power within you.

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This isn’t your standard holiday party. Join RefinedMD on December 4 for a festive evening filled with a little glamour, a little mischief, and plenty of holiday cheer. Stop by the office, grab a cocktail, explore offerings from local vendors, and strike a pose for a photo with our very special sexy Santa. Bring a friend, make it a date night, or simply stop in to celebrate with the RefinedMD team. Expect an evening designed for mingling, shopping, sipping, and kicking off the holiday season in style, all with a distinctly Refined twist. Additional details are coming soon, so save the date and start deciding what you’re going to wear for that Santa photo.

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Choose the area you want to transform, and let’s focus on it. RefinedMD’s CoolSculpting special offers a set package price for a defined body area, including the lower abdomen, full abdomen, flanks, back, neck and chin, or inner or outer thighs. Complete your personalized package within 120 days as our team focuses on helping you achieve visible results in your selected area. It’s a straightforward approach to body contouring: one target area, one package price, and a treatment strategy centered on your goals. Plus, medically eligible patients who purchase a qualifying CoolSculpting package receive 12 weeks of microdosed tirezepatide at no additional cost. Schedule a consultation to determine eligibility and create your transformation plan.

Reviewed for clinical accuracy by a RefinedMD Medical Editor on August 26th, 2026.

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