RefinedMD serves patients throughout the South Bay seeking effective medical weight management. People from Campbell, Saratoga, Cupertino, San Jose, and nearby communities trust our team for advanced options like semaglutide and tirzepatide, along with expert guidance to help them look and feel their best.

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How Do GLP-1 Medications Like Semaglutide Work?

Semaglutide belongs to a class of drugs called GLP-1 receptor agonists, while tirzepatide is a dual GLP-1 and GIP receptor agonist. Both medications work by mimicking the effects of naturally occurring hormones in the body that regulate hunger and promote satiety. By  increasing feelings of fullness, these medications help patients reduce calorie intake and manage their weight more effectively. In clinical studies, patients have experienced an average loss of about 15% of their body weight when combining medication with healthy lifestyle changes, including diet and exercise.

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What Are the Benefits of Semaglutide & Tirzepatide?

Beyond enhancing confidence and self-esteem, GLP-1 medications offer several key health benefits, including:

  • Reduce cravings
  • Stimulates feelings of fullness
  • Regulate blood sugar levels
  • Reduce the risk of cardiovascular disease and other illnesses

Who Is a Good Candidate for GLP-1 Weight Loss Treatment?

Semaglutide and tirzepatide are suitable for men and women aged 40-50 years old who are looking to lose a substantial amount of weight. Patients can expect to lose around 15% of their bodyweight when coupling treatment with healthy habits and sticking to their weekly injections.

Dr. Steven Swengel
Dr. Steven Swengel
Board-Certified Dermatologist

Since establishing RefinedMD in 2012, Dr. Swengel has earned a reputation throughout the South Bay as one of the area’s top cosmetic and medical dermatologists. He is sought out for his expertise as a Mohs micrographic surgeon and laser treatment specialist, as well as his warm, attentive style of patient care.

Meet Dr. Steven Swengel
Dermatologist
Board-Certified Dermatologist

What To Expect During Your Weight Loss Treatment

Our GLP-1 weight loss program is designed to help you lose weight quickly and safely. The process begins with a comprehensive consultation with one of our providers, where we’ll review your medical history and discuss your weight loss goals. You will then receive a customized weight loss treatment plan and information on how to get started.

After receiving your first injection at our office, you will be sent home with the supplies you need to self-inject from the comfort of your home.

How Long Will It Take To Lose Weight With GLP-1s Like Semaglutide?

Though each patient is unique, most will notice weight loss within the first month of treatment. Significant results will be apparent in 4 to 6 months.

What are the Potential Side Effects of Semaglutide and Tirzepatide?

These medications are generally well-tolerated, but the most common side effects include nausea, diarrhea, and sometimes mild indigestion. These symptoms are often temporary and tend to subside as your body adjusts to the treatment.

Does semaglutide or tirzepatide cause hair loss?

Hair thinning is a side effect some people experience while taking semaglutide or tirzepatide. Clinical trials have reported hair loss in a small percentage of patients, with rates varying by medication and sex. Hair shedding may be associated with significant weight loss, although research into the relationship between these medications and hair loss is ongoing.

Do GLP-1 medications make you tired?

Fatigue is a reported side effect for many individuals taking GLP-1 medications. Fluctuating blood sugar levels, dietary changes, and dehydration (especially during the early adjustment period) contribute to tiredness. It’s important to focus on following a nutritious diet and to prioritize sleep.

If any side effects persist or cause discomfort, we encourage you to contact RefinedMD or your primary care physician for assistance.

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Semaglutide & Tirzepatide FAQs

Are semaglutide and tirzepatide weight loss injections safe for everyone?

Not necessarily. Their use should be carefully evaluated and recommended by a health care professional based on an individual’s overall health and weight loss goals.

Is tirzepatide better than semaglutide?

Switching to tirzepatide may be a good solution for some patients who have plateaued during semaglutide treatment, but the treatments are not combined. Your health care provider will monitor your progress and adjust treatment accordingly to help you achieve your weight loss goals.

When will semaglutide begin to suppress my appetite?

Most patients notice reduced cravings and increased feelings of fullness within the first few weeks of treatment. Appetite suppression often becomes more consistent as the medication is gradually increased to the full therapeutic dose.

How long do you stay on semaglutide for weight loss?

Treatment length varies depending on your health, weight loss goals, and how your body responds. Many patients stay on semaglutide long term under medical supervision, since stopping the medication may allow hunger and weight to return.

Does semaglutide have to be refrigerated?

Yes. Semaglutide should be stored in the refrigerator until use to maintain its effectiveness. Once opened, some formulations may remain stable at room temperature for a limited time—your provider will review storage instructions specific to your prescription.

What does it mean to microdose GLP-1s? 

Microdosing refers to using GLP-1 medications at a fraction of the FDA-approved doses. The safety and effectiveness of nonstandard microdosing protocols have not been well established in clinical studies.

Get Started Now

If you’re ready to explore whether you’re a good candidate for semaglutide and tirzepatide treatment in the Los Gatos area, we encourage you to complete the form below or call us at  (408) 688-2082

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Reviewed for clinical accuracy by a RefinedMD Medical Editor on August 26th, 2026.

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